Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 1/20 | 0.55 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.47 |
| ▸ | PLAU | P00749 | 2/20 | 0.46 |
| ▸ | PLG | P00747 | 1/20 | 0.46 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.45 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.45 |
| ▸ | DHODH | Q02127 | 2/20 | 0.44 |
| ▸ | IKBKB | O14920 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29251266 | 1.00 | CTNNB1 (0.55) | CTNNB1SIRT2SIRT1PLAUPLG | |
| SCHEMBL27549107 | 0.89 | CTNNB1 (0.70) | CTNNB1SIRT2SIRT1SCN8ASCN10A | |
| SCHEMBL30974578 | 0.84 | KDM4E (0.46) | PLAUPLGSCN8ASCN10ADHODH | |
| SCHEMBL29250437 | 0.84 | KDM4E (0.46) | PLAUPLGSCN8ASCN10ADHODH | |
| SCHEMBL30974617 | 0.84 | CTNNB1 (0.51) | CTNNB1SIRT2SIRT1IKBKBKDM4E | |
| SCHEMBL29251268 | 0.84 | CTNNB1 (0.51) | CTNNB1SIRT2SIRT1IKBKBKDM4E | |
| SCHEMBL29250441 | 0.83 | CTNNB1 (0.47) | CTNNB1SCN8ASCN10APARP10 | |
| SCHEMBL30974590 | 0.82 | ALDH1A1 (0.50) | CTNNB1SIRT2SIRT1USP2KMT2A | |
| SCHEMBL29250840 | 0.82 | ALDH1A1 (0.50) | CTNNB1SIRT2SIRT1USP2KMT2A | |
| SCHEMBL30974625 | 0.82 | CTNNB1 (0.47) | CTNNB1SIRT2SIRT1SCN8ASCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118084706-A | Synthesis method of 2- (4-hydroxyphenoxy) benzamide compound | 河北科技大学 | 2024-05-28 | — | — | CN | disclosed |