Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | UBE2N | P61088 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27233006 | 0.90 | KDM4E (0.34) | KMT2AKDM4EHPGDLMNAALDH1A1 | |
| SCHEMBL30975932 | 0.86 | KHK (0.30) | — | |
| SCHEMBL27243079 | 0.84 | KDM4E (0.33) | KMT2AKDM4EHPGDLMNAALDH1A1 | |
| SCHEMBL30976021 | 0.82 | LMNA (0.36) | KMT2AKDM4EHPGDLMNAALDH1A1 | |
| SCHEMBL24906279 | 0.82 | KDM4E (0.35) | KMT2AKDM4EHPGDLMNAALDH1A1 | |
| SCHEMBL30951782 | 0.81 | LMNA (0.33) | KDM4EHPGDLMNAALDH1A1MAPT | |
| SCHEMBL30951783 | 0.81 | LMNA (0.33) | KDM4EHPGDLMNAALDH1A1MAPT | |
| SCHEMBL24906332 | 0.81 | LMNA (0.33) | KDM4EHPGDLMNAALDH1A1MAPT | |
| SCHEMBL24906438 | 0.78 | KMT2A (0.33) | KMT2AKDM4EHPGDALDH1A1MAPT | |
| SCHEMBL30107030 | 0.78 | KMT2A (0.33) | KMT2AKDM4EHPGDALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4634159-A1 | SULFOXIMINES AS INHIBITORS OF NAV1.8 | Grünenthal GmbH (DE) | 2025-10-22 | — | — | EP | disclosed |
| WO-2024126648-A1 | SULFOXIMINES AS INHIBITORS OF NaV1.8 | Grünenthal GmbH (DE) | 2024-06-20 | — | — | WO | disclosed |