Sugi Predict

Sugi Predict / Compounds / SCHEMBL30976110

SCHEMBL30976110

SCHEMBL30976110

CCOC(=O)c1c(I)c(C(C)(F)F)nn1CC1(C)CC(F)(F)C1

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 1/20 0.32
▸ ALDH1A1 P00352 1/20 0.32
▸ HPGD P15428 1/20 0.32
▸ MAPK1 P28482 1/20 0.32
▸ KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30975857 0.94 KDM4E (0.32) KDM4EALDH1A1HPGDKMT2A
SCHEMBL30975854 0.92 ALDH1A1 (0.33) KDM4EALDH1A1HPGDMAPK1
SCHEMBL30975893 0.91 KDM4E (0.30) KDM4EALDH1A1HPGD
SCHEMBL24906254 0.89 KDM4E (0.33) KDM4EALDH1A1HPGDMAPK1KMT2A
SCHEMBL30975933 0.88 KDM4E (0.35) KDM4EALDH1A1HPGDMAPK1KMT2A
SCHEMBL27417561 0.84 KDM4E (0.33) KDM4EALDH1A1HPGDMAPK1KMT2A
SCHEMBL30975834 0.83 ALDH1A1 (0.35) KDM4EALDH1A1HPGDMAPK1KMT2A
SCHEMBL30976040 0.83 KDM4E (0.35) KDM4EALDH1A1HPGDMAPK1KMT2A
SCHEMBL24758326 0.82 KMT2A (0.34) KDM4EALDH1A1HPGDMAPK1KMT2A
SCHEMBL24906208 0.82 KDM4E (0.32) KDM4EALDH1A1HPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4634159-A1 SULFOXIMINES AS INHIBITORS OF NAV1.8 Grünenthal GmbH (DE) 2025-10-22 — — EP disclosed
WO-2024126648-A1 SULFOXIMINES AS INHIBITORS OF NaV1.8 Grünenthal GmbH (DE) 2024-06-20 — — WO disclosed