SCHEMBL30976239

SCHEMBL30976239

Cn1nc(Cl)c2cc(F)ccc2c1=O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.45
KDM4E B2RXH2 2/20 0.45
APAF1 O14727 1/20 0.45
HSP90AA1 P07900 1/20 0.45
HSP90AB1 P08238 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
PARG Q86W56 1/20 0.44
SMN1; SMN2 Q16637 4/20 0.41
POLB P06746 2/20 0.41
NR2F2 P24468 1/20 0.41
HTT P42858 1/20 0.41
USP2 O75604 1/20 0.39
LMNA P02545 1/20 0.39
BRD4 O60885 1/20 0.39
ATM Q13315 1/20 0.37
MIF P14174 2/20 0.37
ALDH1A1 P00352 1/20 0.37
TP53 P04637 1/20 0.37
MAPT P10636 1/20 0.37
THRB P10828 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30976297 0.93 PARG (0.50) TSHRKDM4EAPAF1HSP90AA1HSP90AB1
SCHEMBL19770700 0.81 PARG (0.45) PARGSMN1; SMN2LMNAALDH1A1MAPT
SCHEMBL17825009 0.80 PARG (0.44) PARGMIF
SCHEMBL29702206 0.78 KAT2B (0.54) TSHRKDM4EPARGSMN1; SMN2POLB
SCHEMBL17559094 0.78 KAT2B (0.54) TSHRKDM4EPARGSMN1; SMN2POLB
SCHEMBL17559135 0.77 KAT2B (0.50) PARGSMN1; SMN2POLBALDH1A1PKM
SCHEMBL31091769 0.77 KAT2B (0.50) PARGSMN1; SMN2POLBALDH1A1PKM
SCHEMBL4989877 0.76 HPGD (0.52) TSHRKDM4EPARGSMN1; SMN2POLB
SCHEMBL30976508 0.76 SMN1; SMN2 (0.49) TSHRKDM4EAPAF1HSP90AA1HSP90AB1
SCHEMBL30976254 0.76 KDM4E (0.43) TSHRKDM4EAPAF1HSP90AA1HSP90AB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4619387-A1 PHTHALAZINONE BASED MODULATORS FOR THE TREATMENT OF DISEASE Soley Therapeutics, Inc. (US) 2025-09-24 EP disclosed
WO-2024108131-A1 PHTHALAZINONE BASED MODULATORS FOR THE TREATMENT OF DISEASE SOLEY THERAPEUTICS, INC. (US) 2024-05-23 WO disclosed