Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30976257 | 0.82 | ALDH1A1 (0.44) | KMT2AMEN1LMNAPOLBALDH1A1 | |
| SCHEMBL15025470 | 0.81 | KDM4C (0.49) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL29805505 | 0.81 | KDM4C (0.49) | SMN1; SMN2KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL8157443 | 0.79 | KDM4E (0.39) | SMN1; SMN2KMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL3652058 | 0.79 | ALDH1A1 (0.64) | SMN1; SMN2KMT2AMEN1LMNAPOLB | |
| SCHEMBL30976438 | 0.77 | MEN1 (0.57) | SMN1; SMN2KMT2AMEN1LMNAPOLB | |
| SCHEMBL30976239 | 0.76 | TSHR (0.45) | SMN1; SMN2LMNAPOLBALDH1A1PKM | |
| SCHEMBL30976241 | 0.74 | MEN1 (0.50) | SMN1; SMN2KMT2AMEN1LMNAPOLB | |
| SCHEMBL30976297 | 0.73 | PARG (0.50) | SMN1; SMN2POLBTSHRHTTNR2F2 | |
| SCHEMBL30976254 | 0.73 | KDM4E (0.43) | SMN1; SMN2LMNAPOLBALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4619387-A1 | PHTHALAZINONE BASED MODULATORS FOR THE TREATMENT OF DISEASE | Soley Therapeutics, Inc. (US) | 2025-09-24 | — | — | EP | disclosed |
| WO-2024108131-A1 | PHTHALAZINONE BASED MODULATORS FOR THE TREATMENT OF DISEASE | SOLEY THERAPEUTICS, INC. (US) | 2024-05-23 | — | — | WO | disclosed |