Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | DTYMK | P23919 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30976347 | 0.85 | MEN1 (0.69) | POLBDTYMKMEN1KMT2AATM | |
| SCHEMBL30976343 | 0.81 | MEN1 (0.55) | MEN1KMT2AATML3MBTL1ALDH1A1 | |
| SCHEMBL30976476 | 0.80 | MEN1 (0.51) | POLBDTYMKMEN1KMT2AATM | |
| SCHEMBL30976251 | 0.80 | MEN1 (0.51) | POLBDTYMKMEN1KMT2AATM | |
| SCHEMBL30976380 | 0.77 | ALDH1A1 (0.54) | POLBMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL30976335 | 0.77 | MEN1 (0.51) | POLBMEN1KMT2AATML3MBTL1 | |
| SCHEMBL30976409 | 0.77 | MEN1 (0.50) | POLBDTYMKMEN1KMT2AATM | |
| SCHEMBL30976241 | 0.77 | MEN1 (0.50) | POLBMEN1KMT2AATML3MBTL1 | |
| SCHEMBL19377001 | 0.75 | KAT2B (0.67) | DTYMKLMNANPC1NR2F2HTT | |
| SCHEMBL30976294 | 0.74 | KAT2B (0.46) | POLBMEN1KMT2AL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4619387-A1 | PHTHALAZINONE BASED MODULATORS FOR THE TREATMENT OF DISEASE | Soley Therapeutics, Inc. (US) | 2025-09-24 | — | — | EP | disclosed |
| WO-2024108131-A1 | PHTHALAZINONE BASED MODULATORS FOR THE TREATMENT OF DISEASE | SOLEY THERAPEUTICS, INC. (US) | 2024-05-23 | — | — | WO | disclosed |