Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MMP1 | P03956 | 1/20 | 0.52 |
| ▸ | MMP9 | P14780 | 1/20 | 0.52 |
| ▸ | MMP13 | P45452 | 1/20 | 0.52 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3252230 | 0.86 | OPRL1 (0.65) | SIGMAR1CYP2D6TSHRLMNAMEN1 | |
| Hydrochloric Acid SCHEMBL6160179 | 0.85 | POLB (0.66) | SIGMAR1CYP2D6TSHRLMNAMEN1 | |
| SCHEMBL27550808 | 0.85 | OPRL1 (0.63) | SIGMAR1CYP2D6TSHRLMNAMEN1 | |
| SCHEMBL240629 | 0.84 | OPRL1 (0.73) | SIGMAR1CYP2D6TSHRLMNAMEN1 | |
| SCHEMBL654066 | 0.84 | CCR3 (0.68) | SIGMAR1POLB | |
| SCHEMBL1513592 | 0.82 | OPRL1 (0.53) | SIGMAR1CYP2D6TSHRLMNAMEN1 | |
| SCHEMBL15178456 | 0.82 | OPRL1 (0.53) | SIGMAR1CYP2D6TSHRLMNAMEN1 | |
| SCHEMBL28217942 | 0.81 | SIGMAR1 (1.00) | SIGMAR1LMNAMEN1KMT2APOLB | |
| SCHEMBL7016275 | 0.80 | SIGMAR1 (0.72) | SIGMAR1CYP2D6TSHRMEN1KMT2A | |
| SCHEMBL4272060 | 0.78 | SIGMAR1 (0.60) | SIGMAR1CYP2D6TSHRCHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4619387-A1 | PHTHALAZINONE BASED MODULATORS FOR THE TREATMENT OF DISEASE | Soley Therapeutics, Inc. (US) | 2025-09-24 | — | — | EP | disclosed |
| WO-2024108131-A1 | PHTHALAZINONE BASED MODULATORS FOR THE TREATMENT OF DISEASE | SOLEY THERAPEUTICS, INC. (US) | 2024-05-23 | — | — | WO | disclosed |