Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.71 |
| ▸ | DRD2 | P14416 | 1/20 | 0.59 |
| ▸ | HTR2A | P28223 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | HPGDS | O60760 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30976274 | 0.87 | ALDH1A1 (0.53) | NPSR1MAPTSMN1; SMN2LMNAMEN1 | |
| SCHEMBL30976350 | 0.87 | ALDH1A1 (0.53) | NPSR1MAPTLMNAMEN1KMT2A | |
| SCHEMBL30976422 | 0.85 | HTT (0.59) | NPSR1MAPTSMN1; SMN2TP53LMNA | |
| SCHEMBL30976246 | 0.85 | NPSR1 (0.76) | NPSR1DRD2HTR2AMAPTSMN1; SMN2 | |
| SCHEMBL30976393 | 0.84 | MAPT (0.58) | NPSR1MAPTSMN1; SMN2TP53LMNA | |
| SCHEMBL30976461 | 0.83 | NPSR1 (1.00) | NPSR1DRD2HTR2AMAPTSMN1; SMN2 | |
| SCHEMBL30976305 | 0.83 | ALDH1A1 (0.58) | NPSR1MAPTSMN1; SMN2TP53MEN1 | |
| SCHEMBL30976331 | 0.82 | ALDH1A1 (0.62) | NPSR1MAPTLMNAMEN1KMT2A | |
| SCHEMBL30976475 | 0.80 | TP53 (0.57) | NPSR1MAPTSMN1; SMN2TP53LMNA | |
| SCHEMBL30976285 | 0.80 | ALDH1A1 (0.77) | NPSR1MAPTSMN1; SMN2LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4619387-A1 | PHTHALAZINONE BASED MODULATORS FOR THE TREATMENT OF DISEASE | Soley Therapeutics, Inc. (US) | 2025-09-24 | — | — | EP | disclosed |
| WO-2024108131-A1 | PHTHALAZINONE BASED MODULATORS FOR THE TREATMENT OF DISEASE | SOLEY THERAPEUTICS, INC. (US) | 2024-05-23 | — | — | WO | disclosed |