Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CPT2 | P23786 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31199102 | 0.82 | ALDH1A1 (0.55) | ALDH1A1LMNAGAAMAPTTSHR | |
| SCHEMBL30976417 | 0.80 | GBA1 (0.61) | ALDH1A1LMNAGAAMAPTTSHR | |
| SCHEMBL31199155 | 0.80 | ALDH1A1 (0.56) | ALDH1A1LMNAGAAMAPTTSHR | |
| SCHEMBL30976301 | 0.79 | ALDH1A1 (0.53) | ALDH1A1LMNAGAAMAPTTSHR | |
| SCHEMBL30976515 | 0.79 | ALDH1A1 (0.53) | ALDH1A1LMNAGAAMAPTTSHR | |
| SCHEMBL31199212 | 0.78 | TSHR (0.64) | ALDH1A1LMNAGAATSHRPARP1 | |
| SCHEMBL30976303 | 0.78 | ALDH1A1 (0.56) | ALDH1A1LMNAGAAMAPTHPGD | |
| SCHEMBL30976420 | 0.78 | ALDH1A1 (0.56) | ALDH1A1LMNAGAAMAPTTSHR | |
| SCHEMBL30976326 | 0.78 | ALDH1A1 (0.57) | ALDH1A1LMNAGAAMAPTTSHR | |
| SCHEMBL30976308 | 0.78 | ALDH1A1 (0.59) | ALDH1A1LMNAGAAMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4619387-A1 | PHTHALAZINONE BASED MODULATORS FOR THE TREATMENT OF DISEASE | Soley Therapeutics, Inc. (US) | 2025-09-24 | — | — | EP | disclosed |
| WO-2024108131-A1 | PHTHALAZINONE BASED MODULATORS FOR THE TREATMENT OF DISEASE | SOLEY THERAPEUTICS, INC. (US) | 2024-05-23 | — | — | WO | disclosed |