SCHEMBL12414895

SCHEMBL12414895

CCCCN1/C(=C/C=C2\CCCC(/C=C/C3=[N+](CCCC)c4ccc(I)cc4C3(C)C)=C2Cl)C(C)(C)c2cc(I)ccc21

nearest known ligand 0.54

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PRMT1 Q99873 9/20 0.54
PRMT5 O14744 2/20 0.54
PRMT8 Q9NR22 2/20 0.54
CARM1 Q86X55 1/20 0.54
PTPN1 P18031 1/20 0.42
FOLH1 Q04609 3/20 0.39
APP P05067 1/20 0.37
HTR1A P08908 1/20 0.36
FOLR1 P15328 5/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12414867 0.96 PRMT1 (0.54) PRMT1PRMT5PRMT8CARM1PTPN1
SCHEMBL12414855 0.92 PRMT1 (0.50) PRMT1PRMT5PRMT8CARM1PTPN1
SCHEMBL12832513 0.92 PRMT1 (0.56) PRMT1PRMT5PRMT8CARM1PTPN1
SCHEMBL25357251 0.91 PRMT1 (0.66) PRMT1PRMT5PRMT8CARM1PTPN1
SCHEMBL12414894 0.91 PRMT1 (0.66) PRMT1PRMT5PRMT8CARM1PTPN1
SCHEMBL12414904 0.90 PRMT1 (0.46) PRMT1PRMT5PRMT8CARM1PTPN1
SCHEMBL12414903 0.90 PTPN1 (0.55) PRMT1PRMT5PRMT8CARM1PTPN1
Iodide SCHEMBL30976567 0.90 PRMT1 (0.67) PRMT1PRMT5PRMT8CARM1PTPN1
SCHEMBL16000425 0.90 FOLH1 (0.46) PRMT1PRMT5PRMT8CARM1PTPN1
SCHEMBL15033890 0.89 PRMT1 (0.53) PRMT1PRMT5PRMT8CARM1PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110165518-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AGFA GRAPHICS NV (BE) 2011-07-07 US disclosed