Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.77 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | GAPDH | P04406 | 2/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.40 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.40 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.40 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14356269 | 1.00 | ALDH1A1 (0.77) | ALDH1A1HPGDPOLBGAAMAPK1 | |
| SCHEMBL13672343 | 1.00 | ALDH1A1 (0.77) | ALDH1A1HPGDPOLBGAAMAPK1 | |
| SCHEMBL22022494 | 1.00 | ALDH1A1 (0.77) | ALDH1A1HPGDPOLBGAAMAPK1 | |
| SCHEMBL15127532 | 1.00 | ALDH1A1 (0.77) | ALDH1A1HPGDPOLBGAAMAPK1 | |
| SCHEMBL13486952 | 1.00 | ALDH1A1 (0.77) | ALDH1A1HPGDPOLBGAAMAPK1 | |
| SCHEMBL24686427 | 0.91 | ALDH1A1 (0.77) | ALDH1A1HPGDPOLBGAAMAPK1 | |
| SCHEMBL22704385 | 0.91 | ALDH1A1 (0.77) | ALDH1A1HPGDPOLBGAAMAPK1 | |
| SCHEMBL19132639 | 0.91 | ALDH1A1 (0.77) | ALDH1A1HPGDPOLBGAAMAPK1 | |
| SCHEMBL22333897 | 0.91 | ALDH1A1 (0.77) | ALDH1A1HPGDPOLBGAAMAPK1 | |
| SCHEMBL16907937 | 0.91 | ALDH1A1 (0.77) | ALDH1A1HPGDPOLBGAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024107850-A1 | HALO-DEHYDRO-3'-DEOXYURACIL PHOSPHORAMIDATES AND RELATED COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS | ROME THERAPEUTICS, INC. (US) | 2024-05-23 | — | — | WO | disclosed |