Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | LOX | P28300 | 1/20 | 0.44 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | SMARCA2 | P51531 | 4/20 | 0.38 |
| ▸ | SMARCA4 | P51532 | 4/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.37 |
| ▸ | ATR | Q13535 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | PRKACA | P17612 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.35 |
| ▸ | PTPRB | P23467 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22230054 | 1.00 | RECQL (0.47) | RECQLLOXLOXL3LOXL2P2RX3 | |
| SCHEMBL20103538 | 0.86 | RECQL (0.45) | RECQLLOXLOXL3LOXL2P2RX3 | |
| SCHEMBL30935612 | 0.86 | RECQL (0.45) | RECQLLOXLOXL3LOXL2P2RX3 | |
| SCHEMBL23579874 | 0.78 | PTPRB (0.52) | PTPRBTSHR | |
| SCHEMBL12017629 | 0.76 | LOX (0.57) | RECQLLOXLOXL3LOXL2SMARCA2 | |
| SCHEMBL27572843 | 0.75 | RECQL (0.46) | RECQLLOXLOXL3LOXL2DYRK1A | |
| SCHEMBL8268650 | 0.75 | RECQL (0.53) | RECQLLOXLOXL3LOXL2CDK2 | |
| SCHEMBL11509018 | 0.75 | PTPRB (0.47) | PTPRB | |
| SCHEMBL23582543 | 0.75 | CNR2 (0.43) | DYRK1ACYP3A4ROCK1 | |
| SCHEMBL31367160 | 0.75 | RECQL (0.49) | RECQLLOXLOXL3LOXL2DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119112897-A | PCSK9 inhibitors and methods of use thereof | 阿斯利康(瑞典)有限公司 | 2024-12-13 | — | — | CN | disclosed |
| CN-119119023-A | PCSK9 inhibitors and methods of use thereof | 阿斯利康(瑞典)有限公司 | 2024-12-13 | — | — | CN | disclosed |
| CN-119119022-A | PCSK9 inhibitors and methods of use thereof | 阿斯利康(瑞典)有限公司 | 2024-12-13 | — | — | CN | disclosed |
| CN-119060040-A | PCSK9 inhibitors and methods of use thereof | 阿斯利康(瑞典)有限公司 | 2024-12-03 | — | — | CN | disclosed |
| CN-113574055-B | PCSK9 inhibitors and methods of use thereof | 阿斯利康(瑞典)有限公司 | 2024-07-23 | — | — | CN | disclosed |