Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.41 |
| ▸ | LOX | P28300 | 1/20 | 0.41 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.41 |
| ▸ | SMARCA2 | P51531 | 5/20 | 0.40 |
| ▸ | SMARCA4 | P51532 | 4/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.36 |
| ▸ | ATR | Q13535 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22230054 | 0.86 | RECQL (0.47) | RECQLLOXL2LOXLOXL3SMARCA2 | |
| SCHEMBL30977141 | 0.86 | RECQL (0.47) | RECQLLOXL2LOXLOXL3SMARCA2 | |
| SCHEMBL30935612 | 0.78 | RECQL (0.45) | RECQLLOXL2LOXLOXL3SMARCA2 | |
| SCHEMBL31367160 | 0.75 | RECQL (0.49) | RECQLLOXL2LOXLOXL3SMARCA2 | |
| SCHEMBL25388344 | 0.74 | LOXL2 (0.50) | RECQLLOXL2LOXLOXL3SMARCA2 | |
| SCHEMBL31293733 | 0.73 | LOXL2 (0.57) | RECQLLOXL2LOXLOXL3SMARCA2 | |
| SCHEMBL12017629 | 0.73 | LOX (0.57) | RECQLLOXL2LOXLOXL3SMARCA2 | |
| SCHEMBL27572843 | 0.73 | RECQL (0.46) | RECQLLOXL2LOXLOXL3SMARCA2 | |
| SCHEMBL8268650 | 0.73 | RECQL (0.53) | RECQLLOXL2LOXLOXL3SMARCA2 | |
| SCHEMBL20103587 | 0.72 | PTPRB (0.40) | LOXL2ALDH1A1MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018081047-A1 | CYCLOHEXYL GPR40 AGONISTS FOR THE TREATMENT OF TYPE II DIABETES | JANSSEN PHARMACEUTICA NV (BE) | 2018-05-03 | — | — | WO | disclosed |