SCHEMBL30977408

SCHEMBL30977408

C[Si](C)(C)CCc1ccc(C(F)(F)F)cn1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DAO P14920 1/20 0.48
KMT2A Q03164 1/20 0.42
MBOAT4 Q96T53 1/20 0.41
KDM1A O60341 1/20 0.40
MAOA P21397 1/20 0.40
MAOB P27338 1/20 0.40
NPSR1 Q6W5P4 2/20 0.39
KDM4E B2RXH2 1/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
HPGD P15428 1/20 0.38
PDE2A O00408 1/20 0.37
TEAD1 P28347 1/20 0.37
MAPK1 P28482 1/20 0.36
ALDH1A1 P00352 2/20 0.36
PKM P14618 1/20 0.36
TSHR P16473 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
POLB P06746 1/20 0.35
GAA P10253 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29852337 0.81 DAO (0.50) DAOKMT2AMBOAT4KDM1AMAOA
SCHEMBL10115954 0.81 DAO (0.50) DAOKMT2AMBOAT4KDM1AMAOA
SCHEMBL27713067 0.78 DAO (0.50) DAOKMT2AMBOAT4KDM1AMAOA
SCHEMBL1311062 0.78 DAO (0.50) DAOKMT2AMBOAT4KDM1AMAOA
SCHEMBL264652 0.78 TAAR1 (0.52) DAOKMT2AMBOAT4KDM1AMAOA
SCHEMBL31477886 0.78 TAAR1 (0.52) DAOKMT2AMBOAT4KDM1AMAOA
SCHEMBL6836215 0.77 DAO (0.47) DAOKMT2AMBOAT4KDM1AMAOA
SCHEMBL28198578 0.77 DAO (0.47) DAOKMT2AMBOAT4KDM1AMAOA
SCHEMBL14303885 0.77 HRH3 (0.47) DAOKMT2AMBOAT4KDM1AMAOA
SCHEMBL256661 0.77 KMT2A (0.47) DAOKMT2AMBOAT4KDM1AMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4619402-A1 GPR17 MODULATORS AND USES THEREOF Myrobalan Therapeutics, Inc. (US) 2025-09-24 EP disclosed
CN-119613397-A N-heteroaromatic ring-3-sulfonamide compounds and use thereof for preparing GPR17 receptor inhibitors 迈巴制药(南京)有限公司 2025-03-14 CN disclosed
WO-2024104462-A1 GPR17 MODULATORS AND USES THEREOF MYROBALAN THERAPEUTICS NANJING CO. LTD (CN) 2024-05-23 WO disclosed