SCHEMBL30977707

SCHEMBL30977707

CCCCCCC(CSCCCCCC(CCCCCSCC(CCCCCC)OC(=O)CCC1CCCCC1)NCCCCO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C)OC(=O)CCC1CCCCC1

nearest known ligand 0.37

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ KLK7 P49862 5/20 0.37
▸ BCHE P06276 2/20 0.34
▸ TDP1 Q9NUW8 1/20 0.34
▸ TLR2 O60603 5/20 0.33
▸ PPARG P37231 3/20 0.32
▸ ACHE P22303 1/20 0.32
▸ MMP1 P03956 1/20 0.32
▸ MMP3 P08254 1/20 0.32
▸ MMP9 P14780 1/20 0.32
▸ CNR1 P21554 1/20 0.31
▸ CNR2 P34972 1/20 0.31
▸ DAGLA Q9Y4D2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30977717 1.00 KLK7 (0.37) KLK7BCHETDP1TLR2PPARG
SCHEMBL30977742 0.99 KLK7 (0.36) KLK7BCHETDP1TLR2PPARG
SCHEMBL30977701 0.96 KLK7 (0.34) KLK7BCHETDP1TLR2PPARG
SCHEMBL30977769 0.95 KLK7 (0.33) KLK7BCHETDP1TLR2ACHE
SCHEMBL30837979 0.91 TLR2 (0.39) TLR2PPARG
SCHEMBL30977705 0.91 TLR2 (0.39) TLR2PPARG
SCHEMBL30837985 0.91 TLR2 (0.39) TLR2PPARG
SCHEMBL30977723 0.91 TLR2 (0.39) TLR2PPARG
SCHEMBL30838052 0.91 TLR2 (0.39) TLR2PPARG
SCHEMBL30837942 0.91 TLR2 (0.39) TLR2PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4638417-A1 SULFUR-CONTAINING IONIZABLE LIPIDS FOR THE DELIVERY OF NUCLEIC ACIDS AND OTHER THERAPEUTIC AGENTS Nanovation Therapeutics Inc. (CA) 2025-10-29 — — EP disclosed
US-20240398977-A1 SULFUR-CONTAINING IONIZABLE LIPIDS FOR THE DELIVERY OF NUCLEIC ACIDS AND OTHER THERAPEUTIC AGENTS NANOVATION THERAPEUTICS INC. (CA) 2024-12-05 — — US disclosed
US-12121591-B2 Sulfur-containing ionizable lipids for the delivery of nucleic acids and other therapeutic agents NANOVATION THERAPEUTICS INC. (CA) 2024-10-22 — — US disclosed
US-20240261430-A1 SULFUR-CONTAINING IONIZABLE LIPIDS FOR THE DELIVERY OF NUCLEIC ACIDS AND OTHER THERAPEUTIC AGENTS NANOVATION THERAPEUTICS INC. (CA) 2024-08-08 — — US disclosed
WO-2024130421-A1 SULFUR-CONTAINING IONIZABLE LIPIDS FOR THE DELIVERY OF NUCLEIC ACIDS AND OTHER THERAPEUTIC AGENTS NANOVATION THERAPEUTICS INC. (CA) 2024-06-27 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12121591-B2 Sulfur-containing ionizable lipids for the delivery of nucleic acids and other therapeutic agents SLC43A1, NSUN3, NSUN2 KLK7 3697/4885BCHE 3833/4885TDP1 3272/4885
US-20240261430-A1 SULFUR-CONTAINING IONIZABLE LIPIDS FOR THE DELIVERY OF NUCLEIC ACIDS AND OTHER THERAPEUTIC AGENTS SLC43A1, NSUN3, NSUN2 KLK7 3697/4885BCHE 3833/4885TDP1 3272/4885
US-20240398977-A1 SULFUR-CONTAINING IONIZABLE LIPIDS FOR THE DELIVERY OF NUCLEIC ACIDS AND OTHER THERAPEUTIC AGENTS SLC43A1, NSUN3, NSUN2 KLK7 3697/4885BCHE 3833/4885TDP1 3272/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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