Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16316094 | 0.81 | SF3B3 (0.34) | CYP19A1 | |
| SCHEMBL31246344 | 0.75 | SF3B3 (0.32) | — | |
| SCHEMBL29659302 | 0.74 | CYP2D6 (0.43) | CYP2D6CYP2C19CASP1CYP3A4 | |
| SCHEMBL15577083 | 0.63 | CYP2C19 (0.41) | CYP2D6CYP2C19CASP1CYP3A4 | |
| SCHEMBL28362069 | 0.63 | CYP2C19 (0.41) | CYP2D6CYP2C19CASP1CYP3A4 | |
| SCHEMBL30743830 | 0.63 | CYP2C19 (0.41) | CYP2D6CYP2C19CASP1CYP3A4 | |
| SCHEMBL15577084 | 0.63 | CYP2C19 (0.41) | CYP2D6CYP2C19CASP1CYP3A4 | |
| SCHEMBL15616245 | 0.63 | CYP2C19 (0.41) | CYP2D6CYP2C19CASP1CYP3A4 | |
| SCHEMBL15616241 | 0.63 | CYP2C19 (0.41) | CYP2D6CYP2C19CASP1CYP3A4 | |
| SCHEMBL15616243 | 0.63 | CYP2C19 (0.41) | CYP2D6CYP2C19CASP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3801523-B1 | SPLICING MODULATORS | EISAI R&D MAN CO LTD (JP) | 2024-09-11 | — | — | EP | disclosed |
| CN-112367996-B | Methods of using splice modulators | 卫材R&D管理有限公司 | 2024-05-24 | — | — | CN | disclosed |