Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 9/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 2/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21464809 | 0.82 | CYP2D6 (0.36) | CYP2D6CYP3A4CYP2C19CASP1MEN1 | |
| SCHEMBL21464808 | 0.82 | CYP2D6 (0.36) | CYP2D6CYP3A4CYP2C19CASP1MEN1 | |
| SCHEMBL21464901 | 0.81 | CYP2D6 (0.36) | CYP2D6CYP3A4CYP2C19CASP1MEN1 | |
| SCHEMBL21464902 | 0.81 | CYP2D6 (0.36) | CYP2D6CYP3A4CYP2C19CASP1MEN1 | |
| SCHEMBL30978205 | 0.74 | CYP2D6 (0.32) | CYP2D6CYP3A4CYP2C19CASP1 | |
| SCHEMBL30743828 | 0.68 | TSHR (0.40) | CYP2D6CYP3A4CYP2C19CASP1MEN1 | |
| SCHEMBL23404581 | 0.68 | CYP2D6 (0.33) | CYP2D6CYP3A4CYP2C19CASP1ATM | |
| SCHEMBL15577083 | 0.65 | CYP2C19 (0.41) | CYP2D6CYP3A4CYP2C19CASP1MEN1 | |
| SCHEMBL15616245 | 0.65 | CYP2C19 (0.41) | CYP2D6CYP3A4CYP2C19CASP1MEN1 | |
| SCHEMBL15577084 | 0.65 | CYP2C19 (0.41) | CYP2D6CYP3A4CYP2C19CASP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12172988-B2 | Anticancer and antifungal splice modulators | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-12-24 | — | — | US | disclosed |
| US-20220227742-A1 | ANTICANCER AND ANTIFUNGAL SPLICE MODULATORS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2022-07-21 | — | — | US | disclosed |
| EP-4009966-A1 | SCALEABLE PREPARATION OF POLYKETIDES | The Regents of the University of California (US) | 2022-06-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220227742-A1 | ANTICANCER AND ANTIFUNGAL SPLICE MODULATORS | SF3B5, U2AF1, CWC15 | CYP2D6 1956/4885CYP3A4 1106/4885CYP2C19 2104/4885 |
| US-12172988-B2 | Anticancer and antifungal splice modulators | SF3B5, U2AF1, CWC15 | CYP2D6 1956/4885CYP3A4 1106/4885CYP2C19 2104/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.