SCHEMBL30978690

SCHEMBL30978690

CSc1ccc(C(=O)O)c(C)c1Br

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXFP1 Q9HBX9 1/20 0.39
MCL1 Q07820 1/20 0.37
CYP1A2 P05177 1/20 0.37
AR P10275 1/20 0.36
TSHR P16473 2/20 0.35
ALDH1A1 P00352 1/20 0.35
POLB P06746 2/20 0.34
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA4 P22748 1/20 0.34
CA7 P43166 1/20 0.34
CA9 Q16790 1/20 0.34
LCK P06239 1/20 0.34
FYN P06241 1/20 0.34
HAAO P46952 1/20 0.34
GABRP O00591 1/20 0.34
GABRD O14764 1/20 0.34
GABRA1 P14867 1/20 0.34
GABRB1 P18505 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30978692 1.00 RXFP1 (0.39) RXFP1MCL1CYP1A2ARTSHR
SCHEMBL27777699 0.79 CYP1A2 (0.38) MCL1CYP1A2ARTSHRALDH1A1
SCHEMBL6976990 0.78 GABRP (0.42) MCL1CYP1A2TSHRALDH1A1POLB
SCHEMBL7865093 0.78 MCL1 (0.37) RXFP1MCL1CYP1A2ARTSHR
SCHEMBL30978700 0.78 TSHR (0.37) MCL1CYP1A2ARTSHRALDH1A1
SCHEMBL3773890 0.78 TSHR (0.37) MCL1CYP1A2ARTSHRALDH1A1
SCHEMBL286718 0.76 HAAO (0.42) RXFP1MCL1CYP1A2TSHRALDH1A1
SCHEMBL3980826 0.76 CYP1A2 (0.42) RXFP1CYP1A2TSHRALDH1A1LCK
SCHEMBL6981482 0.75 KDM4E (0.39) MCL1CYP1A2ARTSHRALDH1A1
SCHEMBL29102555 0.75 ERN1 (0.38) MCL1CYP1A2ARTSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118373783-A Method for preparing topramezone intermediate dihydro-isoxazole compound 帕潘纳(北京)科技有限公司 2024-07-23 CN disclosed