Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.37 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 3/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30979076 | 0.83 | EGFR (0.42) | TP53POLBTDP1LMNAMAPT | |
| SCHEMBL30979115 | 0.82 | KDM4E (0.46) | TP53POLBTDP1LMNAMAPT | |
| SCHEMBL30979068 | 0.82 | TP53 (0.38) | TP53POLBTDP1CSNK2A1LMNA | |
| SCHEMBL30979104 | 0.82 | TP53 (0.36) | TP53POLBTDP1LMNAMAPT | |
| SCHEMBL30979013 | 0.81 | TP53 (0.43) | TP53POLBTDP1LMNAMAPT | |
| SCHEMBL30978943 | 0.80 | PTAFR (0.38) | TP53POLBTDP1LMNAMAPT | |
| SCHEMBL30979073 | 0.80 | ABCG2 (0.41) | TP53TDP1MAPTKDM4EEGFR | |
| SCHEMBL30979022 | 0.80 | EGFR (0.38) | TP53POLBTDP1LMNAMAPT | |
| SCHEMBL30978940 | 0.79 | LATS1 (0.43) | TP53POLBTDP1CSNK2A1LMNA | |
| SCHEMBL30979121 | 0.79 | KDM1A (0.46) | TP53POLBTDP1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118324767-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2024-07-12 | — | — | CN | disclosed |