Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 7/20 | 0.41 |
| ▸ | IDH2 | P48735 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | MAT2A | P31153 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CTSC | P53634 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30979147 | 0.85 | CACNA1B (0.52) | ABCG2IDH2CACNA1BAPBA1NPSR1 | |
| SCHEMBL30979076 | 0.83 | EGFR (0.42) | ABCG2EGFRKDRMEN1MAPT | |
| SCHEMBL30979115 | 0.82 | KDM4E (0.46) | ABCG2EGFRKDRMEN1MAPT | |
| SCHEMBL30979013 | 0.81 | TP53 (0.43) | ABCG2EGFRKDRMEN1MAPT | |
| SCHEMBL30979029 | 0.80 | TP53 (0.39) | EGFRKDRMAPTKDM4EALDH1A1 | |
| SCHEMBL30978943 | 0.80 | PTAFR (0.38) | ABCG2EGFRKDRMAPTKDM4E | |
| SCHEMBL30979104 | 0.80 | TP53 (0.36) | EGFRKDRMAPTKDM4ETDP1 | |
| SCHEMBL30979022 | 0.80 | EGFR (0.38) | EGFRKDRMEN1MAPTKMT2A | |
| SCHEMBL30978940 | 0.79 | LATS1 (0.43) | ABCG2PDGFRBKDRMEN1MAPT | |
| SCHEMBL30979121 | 0.79 | KDM1A (0.46) | EGFRMEN1MAPTKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118324767-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2024-07-12 | — | — | CN | disclosed |