Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TOP2A | P11388 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30978986 | 0.78 | TOP2A (0.39) | MEN1KMT2ATOP2ASMN1; SMN2KDM4E | |
| SCHEMBL30961058 | 0.77 | KDM4E (0.36) | MEN1KMT2ATOP2ASMN1; SMN2KDM4E | |
| SCHEMBL23601428 | 0.77 | MAT2A (0.48) | SMN1; SMN2HRH4 | |
| SCHEMBL30920847 | 0.76 | KDM4E (0.39) | MEN1KMT2ATOP2ASMN1; SMN2KDM4E | |
| SCHEMBL30961037 | 0.74 | SMN1; SMN2 (0.42) | MEN1KMT2ATOP2ASMN1; SMN2KDM4E | |
| SCHEMBL30979136 | 0.72 | KDM4E (0.36) | TOP2ASMN1; SMN2KDM4ETP53 | |
| SCHEMBL23601386 | 0.69 | EGFR (0.34) | HRH4TP53 | |
| SCHEMBL29909120 | 0.67 | TOP2A (0.54) | MEN1KMT2ATOP2ASMN1; SMN2KDM4E | |
| SCHEMBL22093363 | 0.66 | MAT2A (0.67) | — | |
| SCHEMBL29571368 | 0.66 | MAT2A (0.67) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4081305-B1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES INC (JP) | 2024-09-18 | — | — | EP | disclosed |
| CN-118324767-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2024-07-12 | — | — | CN | disclosed |