Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30978935 | 0.82 | CYP1A1 (0.41) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL30979125 | 0.80 | KDM4E (0.34) | KDM4EALDH1A1MAPT | |
| SCHEMBL30978941 | 0.80 | MAT2A (0.48) | KDM4EALDH1A1HRH3MAPTSMN1; SMN2 | |
| SCHEMBL30978936 | 0.80 | KDM4E (0.34) | KDM4EALDH1A1MAPTTYMSSMN1; SMN2 | |
| SCHEMBL30979084 | 0.80 | TOP2A (0.43) | KDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL29909498 | 0.79 | SMN1; SMN2 (0.46) | KDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL30979120 | 0.78 | HRH4 (0.46) | ALDH1A1ACHEHTTHRH3MAPT | |
| SCHEMBL30961075 | 0.77 | SMN1; SMN2 (0.48) | KDM4EALDH1A1MEN1LMNAHTT | |
| SCHEMBL30013514 | 0.77 | KDM4E (0.35) | KDM4EMEN1F2LMNACHRM2 | |
| SCHEMBL30048544 | 0.74 | MAPT (0.39) | KDM4EMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118324767-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2024-07-12 | — | — | CN | disclosed |