⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13507877 | 0.65 | — | — | |
| Hydrochloric Acid SCHEMBL8632819 | 0.64 | ALDH1A1 (0.33) | — | |
| SCHEMBL14641502 | 0.64 | — | — | |
| SCHEMBL8172874 | 0.62 | — | — | |
| SCHEMBL31539669 | 0.60 | — | — | |
| SCHEMBL2034186 | 0.60 | — | — | |
| SCHEMBL7673672 | 0.60 | — | — | |
| SCHEMBL18300609 | 0.60 | — | — | |
| SCHEMBL295379 | 0.60 | — | — | |
| SCHEMBL7392407 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114127057-B | Phenylaminopyrimidine amide autophagy inhibitors and methods of use thereof | 德西费拉制药有限责任公司 | 2024-07-12 | — | — | CN | claimed |
| CN-114072397-B | Heteroaryl aminopyrimidinamide autophagy inhibitors and methods of use thereof | 德西费拉制药有限责任公司 | 2025-03-28 | — | — | CN | disclosed |