Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | APAF1 | O14727 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30980152 | 0.88 | MEN1 (0.30) | MEN1APAF1NPC1PLA2G1BHSP90AA1 | |
| Hydrochloric Acid SCHEMBL30980128 | 0.81 | NPC1 (0.39) | MEN1APAF1NPC1PLA2G1BHSP90AA1 | |
| SCHEMBL28399994 | 0.80 | NPC1 (0.39) | MEN1APAF1NPC1PLA2G1BHSP90AA1 | |
| SCHEMBL17706421 | 0.79 | NPC1 (0.40) | MEN1APAF1NPC1PLA2G1BHSP90AA1 | |
| Hydrochloric Acid SCHEMBL30980118 | 0.79 | POLB (0.34) | MEN1APAF1NPC1PLA2G1BHSP90AA1 | |
| SCHEMBL17731648 | 0.78 | CA12 (0.33) | MAPTHTTKMT2A | |
| Bromide SCHEMBL19548334 | 0.77 | CA12 (0.32) | MEN1HSP90AA1KMT2ASMN1; SMN2 | |
| Iodide SCHEMBL19548338 | 0.77 | CA12 (0.32) | — | |
| SCHEMBL29724071 | 0.76 | CA1 (0.36) | — | |
| SCHEMBL17731901 | 0.74 | CA12 (0.33) | MEN1HSP90AA1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4622978-A1 | PROCESS FOR THE PRODUCTION OF HYDRIDOSILANES | Momentive Performance Materials GmbH (DE) | 2025-10-01 | — | — | EP | disclosed |
| WO-2024110270-A1 | PROCESS FOR THE PRODUCTION OF HYDRIDOSILANES | MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) | 2024-05-30 | — | — | WO | disclosed |