SCHEMBL30980474

SCHEMBL30980474

CC(=O)N[C@@H]1[C@@H](OCc2ccccc2)[C@@H](OCc2ccccc2)[C@@H](COCc2ccccc2)O[C@@H]1c1cc(COCCOCCNC(=O)OC(C)(C)C)no1

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ PTPN1 P18031 14/20 0.47
▸ CDC25B P30305 13/20 0.47
▸ PTPN2 P17706 7/20 0.47
▸ CDC25A P30304 4/20 0.47
▸ PTPN6 P29350 3/20 0.47
▸ PTPN11 Q06124 3/20 0.47
▸ TP53 P04637 2/20 0.45
▸ MDM2 Q00987 2/20 0.45
▸ MDM4 O15151 1/20 0.45
▸ HSP90AA1 P07900 1/20 0.45
▸ HSP90AB1 P08238 1/20 0.45
▸ BCHE P06276 2/20 0.37
▸ CNR2 P34972 1/20 0.37
▸ NT5E P21589 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30980693 0.84 PTPN1 (0.47) PTPN1CDC25BPTPN2CDC25APTPN6
SCHEMBL30980723 0.81 TP53 (0.45) PTPN1CDC25BPTPN2CDC25APTPN6
SCHEMBL30980528 0.78 TP53 (0.41) PTPN1CDC25BPTPN2CDC25APTPN6
SCHEMBL30980750 0.75 PTPN1 (0.47) PTPN1CDC25BPTPN2CDC25APTPN6
SCHEMBL30980588 0.74 NT5E (0.49) PTPN1CDC25BPTPN2CDC25APTPN6
SCHEMBL24997002 0.73 TACR1 (0.43) PTPN1CDC25BPTPN2CDC25APTPN6
SCHEMBL15514995 0.71 PTPN1 (0.55) PTPN1CDC25BPTPN2CDC25APTPN6
SCHEMBL30980574 0.70 HRAS (0.37) —
SCHEMBL12612570 0.70 PTPN1 (0.50) PTPN1CDC25BPTPN2CDC25APTPN6
SCHEMBL14001397 0.70 PTPN1 (0.50) PTPN1CDC25BPTPN2CDC25APTPN6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4651901-A1 CYCLING LYSOSOMAL TARGETING ANTIBODY CONJUGATES Lycia Therapeutics, Inc. (US) 2025-11-26 — — EP disclosed
EP-4651902-A2 ASGPR BINDING COMPOUNDS AND CONJUGATES Lycia Therapeutics, Inc. (US) 2025-11-26 — — EP disclosed
WO-2024155747-A2 ASGPR BINDING COMPOUNDS AND CONJUGATES LYCIA THERAPEUTICS, INC. (US) 2024-07-25 — — WO disclosed
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