Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.41 |
| ▸ | CDC25B | P30305 | 5/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 4/20 | 0.41 |
| ▸ | CDC25A | P30304 | 3/20 | 0.41 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.40 |
| ▸ | MDM4 | O15151 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | KLK7 | P49862 | 3/20 | 0.39 |
| ▸ | KLK5 | Q9Y337 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.38 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24996998 | 0.88 | SSTR3 (0.49) | TACR1POLBTP53MDM2L3MBTL1 | |
| SCHEMBL30980693 | 0.83 | PTPN1 (0.47) | TACR1POLBPTPN1CDC25BPTPN2 | |
| SCHEMBL24997001 | 0.82 | POLB (0.50) | TACR1POLBPTPN1CDC25BTP53 | |
| SCHEMBL15514995 | 0.79 | PTPN1 (0.55) | PTPN1CDC25BPTPN2CDC25APTPN6 | |
| SCHEMBL16967451 | 0.77 | TP53 (0.55) | POLBPTPN1CDC25BPTPN2PTPN6 | |
| SCHEMBL5840884 | 0.77 | TP53 (0.55) | POLBPTPN1CDC25BPTPN2PTPN6 | |
| SCHEMBL5840927 | 0.77 | TP53 (0.55) | POLBPTPN1CDC25BPTPN2PTPN6 | |
| SCHEMBL15514084 | 0.77 | TP53 (0.55) | POLBPTPN1CDC25BPTPN2PTPN6 | |
| SCHEMBL7582210 | 0.75 | TP53 (0.55) | POLBPTPN1CDC25BPTPN2PTPN6 | |
| SCHEMBL26780343 | 0.74 | LMNA (0.53) | TACR1POLBLMNAKMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023011597-A1 | LIGAND CONJUGATES FOR DELIVERY OF THERAPEUTICALLY ACTIVE AGENTS | Hepagene Therapeutics (HK) Limited (CN) | 2023-02-09 | — | — | WO | disclosed |