Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 2/20 | 0.34 |
| ▸ | TLR1 | Q15399 | 2/20 | 0.34 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.33 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KDM6B | O15054 | 1/20 | 0.32 |
| ▸ | KDM5C | P41229 | 1/20 | 0.32 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.32 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12092180 | 1.00 | TLR2 (0.34) | TLR2TLR1STING1TSHRHDAC3 | |
| SCHEMBL26292093 | 1.00 | TLR2 (0.34) | TLR2TLR1STING1TSHRHDAC3 | |
| SCHEMBL7677587 | 1.00 | TLR2 (0.34) | TLR2TLR1STING1TSHRHDAC3 | |
| SCHEMBL22717025 | 1.00 | TLR2 (0.34) | TLR2TLR1STING1TSHRHDAC3 | |
| SCHEMBL7676443 | 1.00 | TLR2 (0.34) | TLR2TLR1STING1TSHRHDAC3 | |
| SCHEMBL19475654 | 1.00 | TLR2 (0.34) | TLR2TLR1STING1TSHRHDAC3 | |
| SCHEMBL31395742 | 1.00 | TLR2 (0.34) | TLR2TLR1STING1TSHRHDAC3 | |
| SCHEMBL20552587 | 0.98 | STING1 (0.35) | TLR2TLR1STING1TSHRHDAC3 | |
| SCHEMBL27410618 | 0.93 | ALDH1A1 (0.40) | TLR2TLR1TSHRHDAC1HDAC2 | |
| SCHEMBL5735427 | 0.92 | STING1 (0.37) | TLR2TLR1STING1TSHRHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4651902-A2 | ASGPR BINDING COMPOUNDS AND CONJUGATES | Lycia Therapeutics, Inc. (US) | 2025-11-26 | — | — | EP | disclosed |
| WO-2024155747-A2 | ASGPR BINDING COMPOUNDS AND CONJUGATES | LYCIA THERAPEUTICS, INC. (US) | 2024-07-25 | — | — | WO | disclosed |