Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 4/20 | 0.41 |
| ▸ | CA1 | P00915 | 4/20 | 0.41 |
| ▸ | CA2 | P00918 | 4/20 | 0.41 |
| ▸ | CA9 | Q16790 | 4/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | ITK | Q08881 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21106804 | 1.00 | ADRB2 (0.47) | ADRB2HTR1ATDP1MEN1KMT2A | |
| SCHEMBL23728637 | 1.00 | ADRB2 (0.47) | ADRB2HTR1ATDP1MEN1KMT2A | |
| SCHEMBL13114987 | 0.97 | TDP1 (0.47) | ADRB2HTR1ATDP1MEN1KMT2A | |
| SCHEMBL25657888 | 0.89 | ADRB2 (0.44) | ADRB2HTR1ATDP1MEN1KMT2A | |
| SCHEMBL8843547 | 0.88 | TDP1 (0.53) | ADRB2HTR1ATDP1MEN1KMT2A | |
| SCHEMBL22276641 | 0.87 | TDP1 (0.56) | ADRB2HTR1ATDP1MEN1KMT2A | |
| SCHEMBL22276648 | 0.87 | TDP1 (0.56) | ADRB2HTR1ATDP1MEN1KMT2A | |
| SCHEMBL12885084 | 0.87 | TDP1 (0.56) | ADRB2HTR1ATDP1MEN1KMT2A | |
| SCHEMBL27317790 | 0.86 | TDP1 (0.55) | ADRB2HTR1ATDP1MEN1KMT2A | |
| SCHEMBL12079730 | 0.86 | ADRB2 (0.43) | ADRB2HTR1ATDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4651902-A2 | ASGPR BINDING COMPOUNDS AND CONJUGATES | Lycia Therapeutics, Inc. (US) | 2025-11-26 | — | — | EP | disclosed |
| EP-4651901-A1 | CYCLING LYSOSOMAL TARGETING ANTIBODY CONJUGATES | Lycia Therapeutics, Inc. (US) | 2025-11-26 | — | — | EP | disclosed |
| WO-2024155747-A2 | ASGPR BINDING COMPOUNDS AND CONJUGATES | LYCIA THERAPEUTICS, INC. (US) | 2024-07-25 | — | — | WO | disclosed |