SCHEMBL30980743

SCHEMBL30980743

CC(=O)N[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@@H]1CCCCCOCCOCCNC(=O)NCCOCCOCCOCCOCCOCCNC(=O)N1CCN(CCN2C(=O)C=CC2=O)CC1

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ MDK P21741 1/20 0.36
▸ MAPK1 P28482 1/20 0.36
▸ OGA O60502 16/20 0.35
▸ HEXB P07686 12/20 0.34
▸ LGALS3 P17931 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30980785 0.91 MAPK1 (0.37) MDKMAPK1OGAHEXB
SCHEMBL30980555 0.90 MDK (0.37) MDKMAPK1OGAHEXBLGALS3
SCHEMBL30980687 0.88 MAPK1 (0.39) MDKMAPK1OGAHEXBLGALS3
SCHEMBL30980739 0.86 MDK (0.41) MDKMAPK1OGAHEXBLGALS3
SCHEMBL30980636 0.84 MAPK1 (0.36) MDKMAPK1OGALGALS3
SCHEMBL30980534 0.81 MDK (0.38) MDKOGAHEXBLGALS3
SCHEMBL30980784 0.78 MAPK1 (0.38) MDKMAPK1OGAHEXBLGALS3
SCHEMBL30980606 0.77 MAPK1 (0.47) MDKMAPK1OGALGALS3
SCHEMBL30980757 0.76 MAPK1 (0.46) MDKMAPK1LGALS3
SCHEMBL30980642 0.73 MAPK1 (0.43) MDKMAPK1LGALS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4651902-A2 ASGPR BINDING COMPOUNDS AND CONJUGATES Lycia Therapeutics, Inc. (US) 2025-11-26 — — EP disclosed
WO-2024155747-A2 ASGPR BINDING COMPOUNDS AND CONJUGATES LYCIA THERAPEUTICS, INC. (US) 2024-07-25 — — WO disclosed
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