Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MDK | P21741 | 1/20 | 0.34 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 3/20 | 0.31 |
| ▸ | TLR2 | O60603 | 1/20 | 0.31 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.31 |
| ▸ | LGALS3 | P17931 | 2/20 | 0.31 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.31 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
| ▸ | OGA | O60502 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30980687 | 0.88 | MAPK1 (0.39) | MAPK1MDKLGALS3LGALS8LGALS4 | |
| SCHEMBL31384228 | 0.86 | MAPK1 (0.46) | MAPK1MDKTLR2TLR1LGALS3 | |
| SCHEMBL30980743 | 0.84 | MDK (0.36) | MAPK1MDKLGALS3OGA | |
| SCHEMBL30980707 | 0.81 | MAPK1 (0.43) | MAPK1MDKLGALS3LGALS8LGALS4 | |
| SCHEMBL30980773 | 0.77 | MAPK1 (0.40) | MAPK1MDKLGALS3LGALS8LGALS4 | |
| SCHEMBL30980606 | 0.77 | MAPK1 (0.47) | MAPK1MDKLGALS3LGALS8LGALS4 | |
| SCHEMBL30980757 | 0.76 | MAPK1 (0.46) | MAPK1MDKLGALS3LGALS8LGALS4 | |
| SCHEMBL30980522 | 0.75 | MAPK1 (0.43) | MAPK1MDKLGALS3LGALS8LGALS4 | |
| SCHEMBL30980790 | 0.74 | MAPK1 (0.44) | MAPK1MDKLGALS3LGALS8LGALS4 | |
| SCHEMBL30980704 | 0.73 | MAPK1 (0.52) | MAPK1MDKLGALS3LGALS8LGALS4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4651902-A2 | ASGPR BINDING COMPOUNDS AND CONJUGATES | Lycia Therapeutics, Inc. (US) | 2025-11-26 | — | — | EP | disclosed |
| WO-2024155747-A2 | ASGPR BINDING COMPOUNDS AND CONJUGATES | LYCIA THERAPEUTICS, INC. (US) | 2024-07-25 | — | — | WO | disclosed |