Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | WNK1 | Q9H4A3 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28546794 | 1.00 | HCAR3 (0.51) | HCAR3MAPK1PKMRAB9AKDM4E | |
| SCHEMBL24913721 | 1.00 | HCAR3 (0.51) | HCAR3MAPK1PKMRAB9AKDM4E | |
| SCHEMBL21294007 | 0.87 | HCAR3 (0.60) | HCAR3MAPK1PKMRAB9AKDM4E | |
| SCHEMBL29741389 | 0.87 | HCAR3 (0.60) | HCAR3MAPK1PKMRAB9AKDM4E | |
| SCHEMBL20096272 | 0.87 | HCAR3 (0.60) | HCAR3MAPK1PKMRAB9AKDM4E | |
| SCHEMBL21293972 | 0.87 | HCAR3 (0.60) | HCAR3MAPK1PKMRAB9AKDM4E | |
| SCHEMBL17678246 | 0.85 | HCAR3 (0.64) | HCAR3MAPK1PKMRAB9AWNK1 | |
| SCHEMBL17678250 | 0.82 | HCAR3 (0.66) | HCAR3MAPK1WNK1KMT2APSMD14 | |
| SCHEMBL17048217 | 0.82 | HCAR3 (0.66) | HCAR3MAPK1WNK1KMT2APSMD14 | |
| SCHEMBL23177335 | 0.82 | ABCB1 (0.46) | HCAR3MAPK1PKMRAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112574189-B | EP300/CBP inhibitor | 海创药业股份有限公司 | 2024-05-31 | — | — | CN | disclosed |