Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 7/20 | 0.49 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | WNK1 | Q9H4A3 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24913769 | 1.00 | KDM4E (0.51) | KDM4EMAPK1HCAR3MAPTPKM | |
| SCHEMBL23177148 | 1.00 | KDM4E (0.51) | KDM4EMAPK1HCAR3MAPTPKM | |
| SCHEMBL30980960 | 1.00 | KDM4E (0.51) | KDM4EMAPK1HCAR3MAPTPKM | |
| SCHEMBL24913779 | 1.00 | KDM4E (0.51) | KDM4EMAPK1HCAR3MAPTPKM | |
| SCHEMBL18174292 | 0.92 | KDM4E (0.56) | KDM4EMAPK1HCAR3MAPTPKM | |
| SCHEMBL2253578 | 0.90 | KDM4E (0.52) | KDM4EMAPK1HCAR3MAPTPKM | |
| SCHEMBL2251096 | 0.83 | KDM4E (0.53) | KDM4EMAPK1HCAR3MAPTPKM | |
| SCHEMBL2254182 | 0.83 | KDM4E (0.53) | KDM4EMAPK1HCAR3MAPTPKM | |
| SCHEMBL8065851 | 0.83 | KDM4E (0.53) | KDM4EMAPK1HCAR3MAPTPKM | |
| SCHEMBL17678246 | 0.82 | HCAR3 (0.64) | MAPK1HCAR3MAPTPKMRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112574189-B | EP300/CBP inhibitor | 海创药业股份有限公司 | 2024-05-31 | — | — | CN | disclosed |