Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | AAK1 | Q2M2I8 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.35 |
| ▸ | FPR2 | P25090 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18182103 | 1.00 | POLB (0.43) | POLBAAK1CYP3A4CYP2D6KAT2B | |
| SCHEMBL29791970 | 0.91 | AAK1 (0.42) | POLBAAK1CYP3A4CYP2D6KAT2B | |
| SCHEMBL28536643 | 0.91 | AAK1 (0.42) | POLBAAK1CYP3A4CYP2D6KAT2B | |
| SCHEMBL23177340 | 0.91 | AAK1 (0.42) | POLBAAK1CYP3A4CYP2D6KAT2B | |
| SCHEMBL30980984 | 0.91 | AAK1 (0.42) | POLBAAK1CYP3A4CYP2D6KAT2B | |
| SCHEMBL23177128 | 0.91 | AAK1 (0.42) | POLBAAK1CYP3A4CYP2D6KAT2B | |
| SCHEMBL1519578 | 0.88 | POLB (0.43) | POLBCYP3A4CYP2D6KAT2BKDM4E | |
| SCHEMBL29502212 | 0.85 | AAK1 (0.48) | AAK1ALOX15KDM4EGAAMAPT | |
| SCHEMBL459719 | 0.85 | AAK1 (0.48) | AAK1ALOX15KDM4EGAAMAPT | |
| SCHEMBL2946261 | 0.82 | MAPT (0.56) | AAK1ALOX15KDM4EGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112574189-B | EP300/CBP inhibitor | 海创药业股份有限公司 | 2024-05-31 | — | — | CN | disclosed |