Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 5/20 | 0.42 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 6/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | AXL | P30530 | 1/20 | 0.35 |
| ▸ | BPTF | Q12830 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29791970 | 1.00 | AAK1 (0.42) | AAK1RPS6KB1KAT2BHRH4CYP3A4 | |
| SCHEMBL23177340 | 1.00 | AAK1 (0.42) | AAK1RPS6KB1KAT2BHRH4CYP3A4 | |
| SCHEMBL30980984 | 1.00 | AAK1 (0.42) | AAK1RPS6KB1KAT2BHRH4CYP3A4 | |
| SCHEMBL23177128 | 1.00 | AAK1 (0.42) | AAK1RPS6KB1KAT2BHRH4CYP3A4 | |
| SCHEMBL30980977 | 0.91 | POLB (0.43) | AAK1KAT2BHRH4CYP3A4CYP2D6 | |
| SCHEMBL18182103 | 0.91 | POLB (0.43) | AAK1KAT2BHRH4CYP3A4CYP2D6 | |
| SCHEMBL14327261 | 0.81 | AAK1 (0.44) | AAK1CYP3A4CYP2D6 | |
| SCHEMBL29502212 | 0.80 | AAK1 (0.48) | AAK1ALOX15 | |
| SCHEMBL459719 | 0.80 | AAK1 (0.48) | AAK1ALOX15 | |
| SCHEMBL18348307 | 0.80 | NOS3 (0.45) | RPS6KB1KAT2BHRH4CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112574189-B | EP300/CBP inhibitor | 海创药业股份有限公司 | 2024-05-31 | — | — | CN | disclosed |
| CN-112574189-A | EP300/CBP inhibitor | 海创药业股份有限公司 | 2021-03-30 | — | — | CN | disclosed |