Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 0.58 |
| ▸ | TACR1 | P25103 | 15/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 9/20 | 0.44 |
| ▸ | TACR3 | P29371 | 6/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23361960 | 1.00 | GPBAR1 (0.58) | GPBAR1TACR1CYP3A4TACR3 | |
| SCHEMBL23385355 | 0.88 | GPBAR1 (0.53) | GPBAR1TACR1CYP3A4TACR3 | |
| SCHEMBL337412 | 0.82 | GPBAR1 (0.54) | GPBAR1TACR1CYP3A4TACR3 | |
| SCHEMBL336998 | 0.79 | GPBAR1 (0.77) | GPBAR1TACR1CYP3A4TACR3 | |
| SCHEMBL30981003 | 0.79 | GPBAR1 (0.77) | GPBAR1TACR1CYP3A4TACR3 | |
| SCHEMBL30981004 | 0.79 | GPBAR1 (0.77) | GPBAR1TACR1CYP3A4TACR3 | |
| SCHEMBL336672 | 0.79 | GPBAR1 (0.51) | GPBAR1TACR1CYP3A4TACR3 | |
| SCHEMBL16708969 | 0.78 | TACR1 (0.48) | GPBAR1TACR1CYP3A4TACR3 | |
| SCHEMBL1872544 | 0.77 | GPBAR1 (0.74) | GPBAR1TACR1CYP3A4TACR3 | |
| SCHEMBL16001625 | 0.77 | TACR1 (0.46) | TACR1CYP3A4TACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114728906-B | Novel chemical process for preparing the key intermediate 6-chloro-4- (4-fluoro-2-methylphenyl) pyridin-3-amine of NT-814 | 康堤医疗有限公司 | 2024-08-20 | — | — | CN | claimed |
| CN-118496152-A | Novel chemical process for preparing the key intermediate 6-chloro-4- (4-fluoro-2-methylphenyl) pyridin-3-amine of NT-814 | 康堤医疗有限公司 | 2024-08-16 | — | — | CN | claimed |
| CN-114728906-B | Novel chemical process for preparing the key intermediate 6-chloro-4- (4-fluoro-2-methylphenyl) pyridin-3-amine of NT-814 | 康堤医疗有限公司 | 2024-08-20 | — | — | CN | disclosed |
| CN-118496152-A | Novel chemical process for preparing the key intermediate 6-chloro-4- (4-fluoro-2-methylphenyl) pyridin-3-amine of NT-814 | 康堤医疗有限公司 | 2024-08-16 | — | — | CN | disclosed |