SCHEMBL30982174

SCHEMBL30982174

C[Si](C)(C)CCOCn1ncc2nc(Cl)ccc21

nearest known ligand 0.38

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 4/20 0.33
HDAC8 Q9BY41 1/20 0.33
NPC1 O15118 1/20 0.32
F11 P03951 1/20 0.32
MAPT P10636 1/20 0.31
F2RL1 P55085 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27395488 1.00 DGAT1 (0.33) DGAT1HDAC8NPC1F11MAPT
SCHEMBL19948962 0.81 DGAT1 (0.33) DGAT1MAPTF2RL1
SCHEMBL24127736 0.81 DGAT1 (0.34) DGAT1NPC1
SCHEMBL29640102 0.81 DGAT1 (0.45) DGAT1NPC1F2RL1
SCHEMBL16427303 0.80 DGAT1 (0.36) DGAT1NPC1F11MAPTF2RL1
SCHEMBL27395426 0.77 DGAT1 (0.36) DGAT1NPC1F11MAPT
SCHEMBL29626770 0.77 GRIN1 (0.34) DGAT1NPC1MAPTF2RL1
SCHEMBL2598354 0.77 GRIN1 (0.34) DGAT1NPC1MAPTF2RL1
SCHEMBL15400514 0.76 DGAT1 (0.35) DGAT1MAPTF2RL1
SCHEMBL22772858 0.76 DGAT1 (0.34) DGAT1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024123968-A1 RNA TARGETING COMPOUNDS AND USES THEREOF RANAR THERAPEUTICS, INC. (US) 2024-06-13 WO disclosed