Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25901635 | 0.76 | NR1H2 (0.42) | HPGDEPHX1SMN1; SMN2USP2MEN1 | |
| SCHEMBL3461672 | 0.72 | HPGD (0.50) | HPGDEPHX1SMN1; SMN2USP2ALDH1A1 | |
| SCHEMBL21227876 | 0.70 | NR1H2 (0.42) | HSD17B10HPGDCTSKSMN1; SMN2USP2 | |
| SCHEMBL27319966 | 0.70 | NR1H2 (0.42) | HSD17B10HPGDCTSKSMN1; SMN2USP2 | |
| SCHEMBL4629128 | 0.70 | USP2 (0.41) | HSD17B10HPGDEPHX1CTSKSMN1; SMN2 | |
| SCHEMBL24069887 | 0.69 | USP2 (0.46) | HSD17B10HPGDEPHX1CTSKSMN1; SMN2 | |
| SCHEMBL28923159 | 0.69 | USP2 (0.46) | HSD17B10HPGDEPHX1CTSKSMN1; SMN2 | |
| SCHEMBL22595464 | 0.69 | HPGD (0.52) | HPGDEPHX1SMN1; SMN2USP2ALDH1A1 | |
| SCHEMBL17086155 | 0.69 | HSD17B10 (0.38) | HSD17B10HPGDEPHX1SMN1; SMN2MEN1 | |
| SCHEMBL18622465 | 0.69 | NR1H2 (0.36) | HSD17B10HPGDSMN1; SMN2MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024152986-A1 | HETEROARYL AMINO COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF | 北京鞍石生物科技有限责任公司 | 2024-07-25 | — | — | WO | disclosed |