Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 4/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.35 |
| ▸ | DAPK1 | P53355 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30983903 | 0.96 | PIK3CD (0.42) | PIK3CDTLR7DAPK1CYP1A2CYP2C9 | |
| SCHEMBL30983607 | 0.82 | PIK3CD (0.41) | PIK3CDTLR7DAPK1ADORA2AADORA1 | |
| SCHEMBL30983778 | 0.81 | PIK3CD (0.42) | PIK3CDTLR7DAPK1ADORA2AADORA1 | |
| SCHEMBL30983430 | 0.81 | PIK3CD (0.41) | PIK3CDTLR7ADORA2AADORA1 | |
| SCHEMBL30983871 | 0.81 | PIK3CD (0.41) | PIK3CDTLR7 | |
| SCHEMBL30983493 | 0.80 | PIK3CD (0.40) | PIK3CDTLR7 | |
| SCHEMBL30983937 | 0.80 | PIK3CD (0.41) | PIK3CDTLR7DAPK1CYP1A2CYP2C9 | |
| SCHEMBL30983950 | 0.80 | PIK3CD (0.40) | PIK3CDTLR7DAPK1CYP1A2CYP2C9 | |
| SCHEMBL30984101 | 0.79 | ADORA2A (0.56) | PIK3CDADORA2AADORA1 | |
| SCHEMBL30984102 | 0.79 | ADORA2A (0.56) | PIK3CDADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4689155-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | Astrazeneca AB (SE) | 2026-02-11 | — | — | EP | disclosed |
| EP-4630410-A1 | POLQ INHIBITORS | Astrazeneca AB (SE) | 2025-10-15 | — | — | EP | disclosed |
| WO-2024201368-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | ASTRAZENECA AB (SE) | 2024-10-03 | — | — | WO | disclosed |
| WO-2024121753-A1 | POLQ INHIBITORS | ASTRAZENECA AB (SE) | 2024-06-13 | — | — | WO | disclosed |