Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 2/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | HTR1B | P28222 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30983552 | 0.96 | PIK3CD (0.40) | PIK3CDTLR7HRH3HTR1AHTR7 | |
| SCHEMBL30983537 | 0.94 | PIK3CD (0.40) | PIK3CDLTA4HTLR7DRD2SIGMAR1 | |
| SCHEMBL30983453 | 0.93 | PIK3CD (0.39) | PIK3CDLTA4HDRD2HTR1AHTR1D | |
| SCHEMBL30983872 | 0.92 | PIK3CD (0.39) | PIK3CDLTA4HTLR7DRD2HTR1A | |
| SCHEMBL30983413 | 0.90 | SIGMAR1 (0.42) | PIK3CDSIGMAR1HTR1AHTR1DHTR1B | |
| SCHEMBL31269113 | 0.90 | PIK3CD (0.38) | PIK3CDLTA4HTLR7DRD2 | |
| SCHEMBL30983394 | 0.89 | PIK3CD (0.39) | PIK3CDTLR7HRH3SIGMAR1HTR1A | |
| SCHEMBL30983600 | 0.89 | TLR7 (0.44) | PIK3CDTLR7HRH3SIGMAR1HTR1A | |
| SCHEMBL30983607 | 0.89 | PIK3CD (0.41) | PIK3CDTLR7 | |
| SCHEMBL30983804 | 0.88 | TLR7 (0.39) | PIK3CDLTA4HTLR7DRD2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4689155-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | Astrazeneca AB (SE) | 2026-02-11 | — | — | EP | disclosed |
| EP-4630410-A1 | POLQ INHIBITORS | Astrazeneca AB (SE) | 2025-10-15 | — | — | EP | disclosed |
| WO-2024201368-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | ASTRAZENECA AB (SE) | 2024-10-03 | — | — | WO | disclosed |
| WO-2024121753-A1 | POLQ INHIBITORS | ASTRAZENECA AB (SE) | 2024-06-13 | — | — | WO | disclosed |