⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21518279 | 0.84 | — | — | |
| SCHEMBL27951838 | 0.76 | CES2 (0.38) | — | |
| SCHEMBL10049834 | 0.76 | — | — | |
| SCHEMBL18104491 | 0.75 | — | — | |
| SCHEMBL6717923 | 0.75 | — | — | |
| SCHEMBL1695588 | 0.74 | — | — | |
| SCHEMBL9440490 | 0.73 | — | — | |
| SCHEMBL803626 | 0.73 | MGAM (0.39) | — | |
| SCHEMBL1003266 | 0.72 | — | — | |
| SCHEMBL8852752 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150105386-A1 | 4-(4-PYRIDINYL)-BENZAMIDES AND THEIR USE AS ROCK ACTIVITY MODULATORS | ABBVIE DEUTSCHLAND (DE) | 2015-04-16 | — | — | US | disclosed |
| US-8895749-B2 | 4-(4-pyridinyl)-benzamides and their use as rock activity modulators | ABBVIE INC. (US) | 2014-11-25 | — | — | US | disclosed |
| US-20130310378-A1 | 4-(4-PYRIDINYL)-BENZAMIDES AND THEIR USE AS ROCK ACTIVITY MODULATORS | ABBVIE INC. (US) | 2013-11-21 | — | — | US | disclosed |
| US-8445686-B2 | 4-(4-pyridinyl)-benzamides and their use as rock activity modulators | ABBVIE INC. (US) | 2013-05-21 | — | — | US | disclosed |
| US-20100273828-A1 | 4-(4-PYRIDINYL)-BENZAMIDES AND THEIR USE AS ROCK ACTIVITY MODULATORS | ABBVIE DEUTSCHLAND GMBH & CO KG (DE) | 2010-10-28 | — | — | US | disclosed |
| EP-2193119-A1 | 4-(4-PYRIDINYL)-BENZAMIDES AND THEIR USE AS ROCK ACTIVITY MODULATORS | Abbott GmbH & Co. KG (DE) | 2010-06-09 | — | — | EP | disclosed |
| WO-2009027392-A1 | 4-(4-PYRIDINYL)-BENZAMIDES AND THEIR USE AS ROCK ACTIVITY MODULATORS | ABBOTT GMBH & CO. KG (DE) | 2009-03-05 | — | — | WO | disclosed |
| EP-0251114-B1 | THIENOTHIOPHENE DYES | BASF Aktiengesellschaft (DE) | 1990-05-02 | — | — | EP | disclosed |
| US-4843153-A | Azo dyes containing thienothiophene radicals as radicals of the diazo component | BASF AKTIENGESELLSCHAFT (DE) | 1989-06-27 | — | — | US | disclosed |
| EP-0251114-A2 | Thienothiophene dyes | BASF Aktiengesellschaft (DE) | 1988-01-07 | — | — | EP | disclosed |