Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 3/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 4/20 | 0.35 |
| ▸ | CNR2 | P34972 | 4/20 | 0.35 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RARG | P13631 | 1/20 | 0.34 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31268855 | 0.94 | CNR1 (0.38) | PIK3CDNR1I2HSD11B1CNR1 | |
| SCHEMBL31321972 | 0.93 | PIK3CD (0.38) | PIK3CDPDE10ACNR1CNR2 | |
| SCHEMBL30984005 | 0.93 | CFTR (0.40) | PIK3CDPDE10ACNR1CNR2KMT2A | |
| SCHEMBL30983480 | 0.92 | F2 (0.39) | PIK3CDPDE10ACNR1CNR2 | |
| SCHEMBL31321968 | 0.92 | MAPK14 (0.40) | PIK3CDPDE10ACNR1CNR2 | |
| SCHEMBL30983776 | 0.89 | PIK3CD (0.40) | PIK3CDPDE10ACNR1CNR2KMT2A | |
| SCHEMBL31269475 | 0.88 | PIK3CD (0.37) | PIK3CDNR1I2HSD11B1EGLN2EGLN1 | |
| SCHEMBL30983826 | 0.88 | PIK3CD (0.39) | PIK3CDPDE10ACNR1CNR2KMT2A | |
| SCHEMBL31269290 | 0.87 | PIK3CD (0.37) | PIK3CDPDE10ACNR1CNR2 | |
| SCHEMBL30983784 | 0.87 | PIK3CD (0.40) | PIK3CDPDE10ACNR1CNR2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4689155-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | Astrazeneca AB (SE) | 2026-02-11 | — | — | EP | disclosed |
| EP-4630410-A1 | POLQ INHIBITORS | Astrazeneca AB (SE) | 2025-10-15 | — | — | EP | disclosed |
| WO-2024201368-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | ASTRAZENECA AB (SE) | 2024-10-03 | — | — | WO | disclosed |
| WO-2024121753-A1 | POLQ INHIBITORS | ASTRAZENECA AB (SE) | 2024-06-13 | — | — | WO | disclosed |