Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 2/20 | 0.40 |
| ▸ | DAPK1 | P53355 | 3/20 | 0.37 |
| ▸ | CNR1 | P21554 | 5/20 | 0.36 |
| ▸ | CNR2 | P34972 | 3/20 | 0.36 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | GALR3 | O60755 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30983850 | 0.93 | CNR1 (0.40) | PIK3CDCNR1PDE10A | |
| SCHEMBL30983826 | 0.90 | PIK3CD (0.39) | PIK3CDDAPK1CNR1CNR2NR2F2 | |
| SCHEMBL30983784 | 0.89 | PIK3CD (0.40) | PIK3CDDAPK1CNR1CNR2NR2F2 | |
| SCHEMBL30983906 | 0.89 | PIK3CD (0.39) | PIK3CDDAPK1CNR1CNR2MEN1 | |
| SCHEMBL30983797 | 0.88 | PIK3CD (0.39) | PIK3CDDAPK1CNR1CNR2NR2F2 | |
| SCHEMBL30983817 | 0.88 | CNR1 (0.41) | PIK3CDCNR1CNR2KMT2APDE10A | |
| SCHEMBL31321972 | 0.87 | PIK3CD (0.38) | PIK3CDCNR1CNR2ADORA2AADORA1 | |
| SCHEMBL30983779 | 0.87 | KCNH2 (0.36) | PIK3CDCNR1 | |
| SCHEMBL30983827 | 0.87 | PIK3CD (0.38) | PIK3CDDAPK1CNR1CNR2NR2F2 | |
| SCHEMBL30983807 | 0.87 | PIK3CD (0.35) | PIK3CDCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4689155-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | Astrazeneca AB (SE) | 2026-02-11 | — | — | EP | disclosed |
| EP-4630410-A1 | POLQ INHIBITORS | Astrazeneca AB (SE) | 2025-10-15 | — | — | EP | disclosed |
| WO-2024201368-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | ASTRAZENECA AB (SE) | 2024-10-03 | — | — | WO | disclosed |
| WO-2024121753-A1 | POLQ INHIBITORS | ASTRAZENECA AB (SE) | 2024-06-13 | — | — | WO | disclosed |