Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | PI4KA | P42356 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.37 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.37 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.37 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30984000 | 0.81 | CYP2C19 (0.61) | CYP2C19ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL31269439 | 0.81 | CYP2C19 (0.60) | CYP2C19ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL6664608 | 0.77 | ADORA3 (0.47) | CYP2C19ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL17847680 | 0.69 | CCNB2 (0.43) | CYP2C19ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL17847685 | 0.68 | NPC1 (0.41) | CYP2C19ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL17847688 | 0.68 | NPC1 (0.41) | CYP2C19ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL21684666 | 0.68 | NPC1 (0.42) | CYP2C19TP53CYP2C9NFKB1MAPK1 | |
| SCHEMBL17847268 | 0.68 | NPC1 (0.67) | ADORA3ADORA2AADORA1ADORA2BTP53 | |
| SCHEMBL30984101 | 0.67 | ADORA2A (0.56) | ADORA2AADORA1ADORA2BPIK3CD | |
| SCHEMBL30984102 | 0.67 | ADORA2A (0.56) | ADORA2AADORA1ADORA2BPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4630410-A1 | POLQ INHIBITORS | Astrazeneca AB (SE) | 2025-10-15 | — | — | EP | disclosed |
| WO-2024121753-A1 | POLQ INHIBITORS | ASTRAZENECA AB (SE) | 2024-06-13 | — | — | WO | disclosed |