Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
| ▸ | PDE1B | Q01064 | 3/20 | 0.39 |
| ▸ | HTR6 | P50406 | 2/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.37 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30984067 | 0.83 | CNR1 (0.40) | CNR1PDE1BHTR6HPGDALDH1A1 | |
| SCHEMBL30983809 | 0.79 | TLR7 (0.38) | CNR1HPGDKDM4ETDP1 | |
| SCHEMBL30984013 | 0.79 | CNR1 (0.34) | CNR1PDE10AKMT2AMEN1NR2F2 | |
| SCHEMBL30983784 | 0.74 | PIK3CD (0.40) | CNR1ADORA2AADORA1PDE10AKMT2A | |
| SCHEMBL30983850 | 0.71 | CNR1 (0.40) | CNR1PDE1BHTR6HPGDALDH1A1 | |
| SCHEMBL30983966 | 0.71 | MEN1 (0.46) | ADORA2AADORA1ALDH1A1KDM4EHTT | |
| SCHEMBL5237151 | 0.68 | CNR1 (0.71) | CNR1KMT2A | |
| SCHEMBL30983849 | 0.67 | CNR1 (0.40) | CNR1KDM4ETDP1KMT2AMEN1 | |
| SCHEMBL24569797 | 0.66 | CNR1 (0.56) | CNR1 | |
| SCHEMBL30984055 | 0.66 | KMT2A (0.48) | ADORA2AADORA1HPGDALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4630410-A1 | POLQ INHIBITORS | Astrazeneca AB (SE) | 2025-10-15 | — | — | EP | disclosed |
| WO-2024121753-A1 | POLQ INHIBITORS | ASTRAZENECA AB (SE) | 2024-06-13 | — | — | WO | disclosed |