Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 4/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | SCN1A | P35498 | 1/20 | 0.34 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.34 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30983784 | 0.93 | PIK3CD (0.40) | CNR1SLC6A4PDE10APIK3CD | |
| SCHEMBL30983850 | 0.90 | CNR1 (0.40) | CNR1HTR6PDE10APIK3CDPDE1B | |
| SCHEMBL31268855 | 0.87 | CNR1 (0.38) | CNR1HTR6PIK3CDPDE1BSCN1A | |
| SCHEMBL31269133 | 0.86 | PLA2G2A (0.38) | CNR1HTR6PDE10APIK3CDPDE1B | |
| SCHEMBL30983914 | 0.84 | CNR1 (0.35) | CNR1SLC6A4PIK3CDKCNH2KDM4E | |
| SCHEMBL30983829 | 0.84 | KCNH2 (0.34) | CNR1PDE10APIK3CDKCNH2 | |
| SCHEMBL30983403 | 0.84 | CNR1 (0.36) | CNR1HTR6PIK3CDHTR1ADRD2 | |
| SCHEMBL30984047 | 0.83 | CNR1 (0.44) | CNR1HTR6PDE10APDE1BCXCR2 | |
| SCHEMBL30983776 | 0.82 | PIK3CD (0.40) | CNR1PDE10APIK3CD | |
| SCHEMBL30983937 | 0.82 | PIK3CD (0.41) | CNR1PDE10APIK3CDTLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4630410-A1 | POLQ INHIBITORS | Astrazeneca AB (SE) | 2025-10-15 | — | — | EP | disclosed |
| WO-2024121753-A1 | POLQ INHIBITORS | ASTRAZENECA AB (SE) | 2024-06-13 | — | — | WO | disclosed |