Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 6/20 | 0.36 |
| ▸ | AR | P10275 | 5/20 | 0.36 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.34 |
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30985019 | 0.89 | PDE3B (0.44) | KCNH2SOS1NR3C1PGRSLC6A4 | |
| SCHEMBL30984927 | 0.85 | SOS1 (0.41) | CCR3KCNH2HRH1CRBNAR | |
| SCHEMBL30984839 | 0.83 | DDB1 (0.38) | CRBNDDB1POLB | |
| SCHEMBL30984936 | 0.78 | DDB1 (0.38) | CRBNDDB1 | |
| SCHEMBL30985126 | 0.74 | CCR3 (0.40) | CCR3CRBNARDDB1BDKRB1 | |
| SCHEMBL30985135 | 0.74 | SOS1 (0.45) | CCR3SOS1 | |
| SCHEMBL30984770 | 0.74 | SOS1 (0.36) | CCR3CRBNARDDB1SOS1 | |
| SCHEMBL30984766 | 0.74 | SOS1 (0.36) | CCR3CRBNARDDB1SOS1 | |
| SCHEMBL27123730 | 0.73 | GABRD (0.43) | CRBNDDB1 | |
| SCHEMBL27292808 | 0.73 | CRBN (0.61) | CRBNDDB1ESR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024146502-A1 | WEE1 DEGRADING COMPOUNDS | BEIJING NEOX BIOTECH LIMITED (CN) | 2024-07-11 | — | — | WO | disclosed |