Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 16/20 | 0.47 |
| ▸ | IKZF2 | Q9UKS7 | 3/20 | 0.42 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.42 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.42 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.41 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20231914 | 0.90 | CRBN (0.53) | CRBNIKZF2IKZF1DDB1IKZF3 | |
| SCHEMBL29546738 | 0.90 | CRBN (0.53) | CRBNIKZF2IKZF1DDB1IKZF3 | |
| SCHEMBL30984707 | 0.87 | CRBN (0.61) | CRBNDDB1IKZF3CYP11B2 | |
| SCHEMBL30984958 | 0.86 | CRBN (0.51) | CRBNIKZF2IKZF1DDB1IKZF3 | |
| SCHEMBL22581040 | 0.86 | CRBN (0.47) | CRBNIKZF2IKZF1DDB1IKZF3 | |
| SCHEMBL26609638 | 0.86 | CRBN (0.51) | CRBNIKZF2IKZF1DDB1IKZF3 | |
| SCHEMBL25133772 | 0.86 | CRBN (0.46) | CRBNIKZF2IKZF1DDB1IKZF3 | |
| SCHEMBL29927740 | 0.86 | CRBN (0.46) | CRBNIKZF2IKZF1DDB1IKZF3 | |
| SCHEMBL25133245 | 0.84 | IKZF2 (0.50) | CRBNIKZF2IKZF1DDB1IKZF3 | |
| SCHEMBL24718660 | 0.84 | IKZF2 (0.48) | CRBNIKZF2IKZF1DDB1IKZF3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024146502-A1 | WEE1 DEGRADING COMPOUNDS | BEIJING NEOX BIOTECH LIMITED (CN) | 2024-07-11 | — | — | WO | disclosed |