Aminometradine

Aminometradine

SCHEMBL309849

C=CCn1c(N)cc(=O)n(CC)c1=O

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.48
KMT2A Q03164 2/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
GAA P10253 3/20 0.42
ADORA2B P29275 3/20 0.40
ADORA2A P29274 2/20 0.40
PDE4A P27815 1/20 0.40
PDE4B Q07343 1/20 0.40
PDE4C Q08493 1/20 0.40
PDE4D Q08499 1/20 0.40
ALDH1A1 P00352 3/20 0.39
MAPT P10636 2/20 0.39
KDM4E B2RXH2 2/20 0.39
GFER P55789 1/20 0.39
APLNR P35414 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
TSHR P16473 1/20 0.38
FPR1 P21462 1/20 0.38
NPSR1 Q6W5P4 1/20 0.37
USP2 O75604 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28968573 0.93 CYP3A4 (0.48) CYP3A4KMT2ASMN1; SMN2GAAADORA2B
SCHEMBL476495 0.90 CYP3A4 (0.56) CYP3A4KMT2ASMN1; SMN2GAAADORA2B
SCHEMBL2329963 0.84 ALDH1A1 (0.47) CYP3A4GAAADORA2BADORA2AALDH1A1
SCHEMBL3983345 0.81 GAA (0.43) CYP3A4KMT2ASMN1; SMN2GAAADORA2B
SCHEMBL5613156 0.80 CYP3A4 (0.44) CYP3A4KMT2ASMN1; SMN2GAAADORA2B
SCHEMBL4189223 0.76 HPGD (0.46) CYP3A4KMT2ASMN1; SMN2GAAALDH1A1
SCHEMBL10897138 0.76 CYP3A4 (0.42) CYP3A4KMT2ASMN1; SMN2GAAADORA2B
SCHEMBL9246057 0.76 CYP3A4 (0.76) CYP3A4KMT2ASMN1; SMN2GAAADORA2B
SCHEMBL4106167 0.76 CYP3A4 (0.76) CYP3A4KMT2ASMN1; SMN2GAAADORA2B
SCHEMBL239409 0.74 ALDH1A1 (0.45) CYP3A4GAAADORA2BADORA2APDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 822 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109134567-A A kind of fermentation preparation of ucleosides antimicrobial compound 中国科学院成都生物研究所 2019-01-04 CN claimed
CN-108508202-A A kind of methods and applications of hypersensitive, multi-residue determination Advanced glycation endproducts 南京师范大学 2018-09-07 CN claimed
CN-108277257-A A kind of culture medium 深圳市伯劳特生物制品有限公司 2018-07-13 CN claimed
CN-105733385-B A kind of bionical water paint and preparation method thereof of keeping a public place clean 泉州三欣新材料科技有限公司 2017-12-01 CN claimed
CN-106987170-A Coating and printing ink auxiliary agent that a kind of graphene is modified and preparation method thereof 广州市侗富贵化工原材料有限公司 2017-07-28 CN claimed
CN-105733385-A Bionic cleaning water-based paint and preparation method thereof 泉州三欣新材料科技有限公司 2016-07-06 CN claimed
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
EP-2560634-A1 NITRIC OXIDE RELEASING PRODRUGS OF THERAPEUTIC AGENTS Piramal Enterprises Limited (IN) 2013-02-27 EP claimed
CN-101486863-B Environment friendly waterborne paint and preparation thereof SHENZHEN OCEANPOWER IND CO LTD 2012-12-12 CN claimed
CN-102792162-A Method for detecting prediabetes UNIV FUKUOKA 2012-11-21 CN claimed
EP-1087953-B1 NITRATE SALTS OF ANTIHYPERTENSIVE MEDICINES NICOX SA (FR) 2004-11-17 EP claimed
CN-1294519-A Pharmaceutical composition containing a compound having an activity of promoting the absorption of an active ingredient INPHARMA SA (CH) 2001-05-09 CN claimed
EP-1087953-A1 NITRATE SALTS OF ANTIHYPERTENSIVE MEDICINES NICOX S.A. (FR) 2001-04-04 EP claimed
EP-1073470-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2001-02-07 EP claimed
WO-2000048636-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2000-08-24 WO claimed
CN-1054745-C Antibiotic combination HOFFMANN LA ROCHE (CH) 2000-07-26 CN claimed
WO-1999067231-A1 NITRATE SALTS OF ANTIHYPERTENSIVE MEDICINES NICOX S.A. (FR) 1999-12-29 WO claimed
CN-1119104-A 'Yanchuanning' injection for curing animal asthma and preparing process thereof LIU FANGGE (CN) 1996-03-27 CN claimed
CN-1105563-A Antibiotic combination HOFFMANN LA ROCHE (CH) 1995-07-26 CN claimed
US-4557934-A ALONG WITH A DIOL PYRROLIDONE OR AN AZACYCLOPENTAN-2-ONE THE PROCTER & GAMBLE COMPANY (US) 1985-12-10 US claimed