Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 8/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 8/20 | 0.46 |
| ▸ | GABRD | O14764 | 2/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30984936 | 0.83 | DDB1 (0.38) | DDB1CRBNGABRDGABRA1GABRB1 | |
| SCHEMBL31678103 | 0.81 | DDB1 (0.53) | DDB1CRBNGABRDGABRA1GABRB1 | |
| SCHEMBL31255522 | 0.75 | DDB1 (0.46) | DDB1CRBN | |
| SCHEMBL30731869 | 0.74 | DDB1 (0.45) | DDB1CRBNMAPK1MEN1KMT2A | |
| SCHEMBL24848415 | 0.73 | CRBN (0.57) | DDB1CRBN | |
| SCHEMBL31382060 | 0.73 | CRBN (0.57) | DDB1CRBN | |
| SCHEMBL30643566 | 0.73 | CRBN (0.57) | DDB1CRBN | |
| SCHEMBL26641203 | 0.73 | CRBN (0.57) | DDB1CRBN | |
| SCHEMBL30706220 | 0.73 | DDB1 (0.65) | DDB1CRBN | |
| SCHEMBL26925285 | 0.73 | DDB1 (0.65) | DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024146502-A1 | WEE1 DEGRADING COMPOUNDS | BEIJING NEOX BIOTECH LIMITED (CN) | 2024-07-11 | — | — | WO | disclosed |