Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 10/20 | 0.53 |
| ▸ | CRBN | Q96SW2 | 10/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | GABRD | O14764 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31255522 | 0.88 | DDB1 (0.46) | DDB1CRBN | |
| SCHEMBL30731869 | 0.87 | DDB1 (0.45) | DDB1CRBN | |
| Hydrochloric Acid SCHEMBL26924650 | 0.86 | DDB1 (0.44) | DDB1CRBN | |
| Hydrochloric Acid SCHEMBL30706112 | 0.86 | DDB1 (0.44) | DDB1CRBN | |
| SCHEMBL31232873 | 0.85 | CRBN (0.52) | DDB1CRBNSIGMAR1EPHX2GABRD | |
| SCHEMBL30984912 | 0.81 | DDB1 (0.46) | DDB1CRBNGABRDGABRA1GABRB1 | |
| SCHEMBL30706220 | 0.80 | DDB1 (0.65) | DDB1CRBN | |
| SCHEMBL26925285 | 0.80 | DDB1 (0.65) | DDB1CRBN | |
| SCHEMBL28978035 | 0.80 | DDB1 (0.44) | DDB1CRBNSIGMAR1 | |
| SCHEMBL31678136 | 0.79 | DDB1 (0.66) | DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250270191-A1 | QUINOLONE BCL6 BIFUNCTIONAL DEGRADERS | Treeline Biosciences, Inc. | 2025-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250270191-A1 | QUINOLONE BCL6 BIFUNCTIONAL DEGRADERS | BCL6, BCL6B, BCOR | DDB1 141/4885CRBN 756/4885SIGMAR1 4241/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.